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Shingles, also known as herpes zoster, is a viral infection caused by the reactivation of the varicella-zoster virus (VZV), the same virus responsible for chickenpox. Once a person recovers from chickenpox, the virus remains dormant in nerve tissues and can reactivate years or even decades later, leading to shingles. This condition is characterized by a painful rash that typically appears on one side of the body or face, often in a band-like pattern. While shingles is not a life-threatening illness, it can cause significant discomfort and, in some cases, lead to long-term complications such as postherpetic neuralgia (PHN), a persistent nerve pain that can last for months or even years after the rash has healed.
The history of shingles dates back to ancient times, with early descriptions found in medical texts from different cultures. However, it was not until the 20th century that researchers discovered its link to the varicella-zoster virus. The introduction of the chickenpox vaccine in the 1990s significantly reduced the number of new chickenpox cases, which in turn is expected to lower the incidence of shingles over time. Nevertheless, shingles remains a common condition, particularly among older adults and individuals with weakened immune systems.
Understanding who is at risk for shingles is essential for prevention and early intervention. While anyone who has had chickenpox can develop shingles, the likelihood increases with age. The immune system naturally weakens as people grow older, making those over the age of 50 particularly vulnerable. Individuals with compromised immune systems, such as those undergoing chemotherapy, people with HIV/AIDS, or patients on long-term immunosuppressive medications, are also at an increased risk. Additionally, factors such as stress, chronic illness, and certain medical conditions can contribute to the reactivation of the virus.
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Audiobook: February 27, 2025
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